A killer flu has swept the world. Survival is key. In a city soon to be deserted by the military, a group of lottery winners get to take the last bus out. The armored vehicle will take them to a government shelter. The trip won't be easy. Along the way they will have to face roving gangs and warlords. 

Among the passengers on the bus is a young woman carrying the fate of the world in her hands. People will kill to get their hands on what she's carrying. The passengers will have to band together if they're going to survive the last ride to safety.