After years of emotional abuse, Reuben Petteway is a lonely and angry young man. With an IQ in the top 2%, he is also a near-genius. When he is pulled aside and strip searched while waiting to board a flight at Cleveland Hopkins International Airport, Reuben goes over the edge and his anger turns to rage. Add a synthetic drug known as Spice to the mix and the result is a violent and unpredictable psychotic who will stop at nothing to get his revenge. His weapon is Madroxapin, an antipsychotic medication used in the treatment of schizophrenia and bipolar disorder. It was introduced in 1972 and reclassified three years later as a "last resort medication" after it was shown to cause a dangerous decrease in white blood cells. Madroxapin is used only in patients that have not responded to other anti-psychotic drugs. It can cause severe side effects including bowel infarction, epileptic-type seizures, bloating, and bleeding from the eyes, ears and nose. Madroxapin ingestion by non-psychotics results in a delayed, but violent reaction similar to cyanide poisoning which rapidly halts cellular respiration and is almost always fatal.