For generations the discoveries of science tended to challenge the very existence of God. Templeton makes a striking argument for just the opposite point of view. He goes to the writings of many of the world's leading scientific thinkers—as diverse in background as Albert Einstein and Teilhard de Chardin—and discovers them in awe of the universe, perceiving the hand of Divine mystery at work.

The Humble Approach teaches that man can discover and comprehend only a few of the infinite aspects of God's nature, never enough to form a comprehensive theology. The humble approach may be a science still in its infancy, but it seeks to develop a way of knowing God appropriate to His greatness and our littleness.