Antonella Amoruso, senior deputy of Milan's anti-terrorism police, receives a call to return to her Naples hometown for the funeral of a family member murdered in a Camorra clan feud.

Amoruso is plunged into the dangerous culture of Camorra, Naple's violent criminal syndicate, that thrives on illegal drugs, prostitution, extortion, and murder. Her goal is to rescue her family from Camorra's deadly grip.