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Proteogenomics examines various aspects of technologies thathave been adopted in the field of Proteogenomics. It includes the meaning of Proteogenomics and various tools required tohave an in-depth understanding of these kinds of studies. Providethe reader with the insights into the development of biologicalresearch which would help in utilizing the combination ofproteomics, genomics, and transcriptomics to aid in the discoveryand identification of peptides.