Headstrong nurse Davie Penrose has moved to London from a small village in Cornwall to start work in the children's transplant ward. He left to progress his career, but also to escape the painful memories of his ex-boyfriend, a workaholic doctor.

Ambitious Doctor Leo Westbury is in charge of a ward for now, but he has plans to be a medical director soon. Making use of his charm and avoiding commitment due to a painful past, he enjoys temporary relationships with male student nurses.

Clashing over a request to look around the ward before he starts work, Davie thinks Leo pompous, while Leo finds Davie bossy. Becoming friends over a shared passion for helping children on their transplant wards, they get closer through the inevitable ups and downs of caring for sick children. Physical attraction pulls them together; their pasts push them apart.

Both damaged and hurt in different ways, they might just find their happy ever after together.