Dr. Jeronimus Quint has an unusual business model that Hippocrates would frown upon: he creates his own patients by injuring people whose lives then depend on him. His latest victims are Jonas Crow, Undertaker, and Rose, his English companion. Without the best medical attention—i.e. Quint's—each might lose a limb, or even die, from gangrene. He's kidnapped Rose and is withholding his sado-surgical skills while Jonas and his cohort Lin pursue him and his captive. With ferrymen and lumberjacks in front, angry lawmen behind, and a leg killing him from within, the Undertaker hopes to survive long enough to make Jeronimus Quint his next customer.