This book deals extensively with theoretical, empirical, and robust methodology of capital structure in the context of debt structure in the Ghanaian financial sector. The study investigated the relationship between debt structure and financial performance of financial institutions in Ghana over the period 20022011. Using panel data methodology, it was discovered that there is a significant difference in the capital structure practices of insurance companies and banks. Short-term debts and total debt are negatively significant in determining returns on equity (ROE) and returns on asset (ROA) in the financial institutions of Ghana.