As predicted in the Ghost Dance Vision, life has come full circle in 2054. The Blackfeet now control Yellowstone National Park, where the buffalo have multiplied, as have the people themselves.

Outside the Indian lands thousands are dying of Quake Fever every day. Doctor Alcina Hancock struggles to find a cure before her mother dies. Thrust into the world of the Indians, she not only discovers what it will take to save her people, but also herself.

Ekuskini, son of the Blackfeet chief, revels in the demise of the non-Indian. Then he meets Alcina and finds himself searching the old ones for the answers. Together Alcina and Ekuskini realize they must learn from the past and use it to make things better for the future of all people.