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This cornerstone reference demonstrates that cellular and intracellular membranes are active in every aspect of the body’s physiology and pathophysiology, comparing secondary through quaternary structures and protein sequences, and gauging their influence on health, disease, and drug therapy.
Highlights the importance of correlations, homologies, and categorizing mulifunctionality by domain and complex!
With the contributions of over 60 experts from countries that span the globe, Membrane Structure in Disease and Drug Therapy
- describes interaction with membranous transport systems
- details reactions with membrane-imbedded receptors
- discusses activation or inhibition of membrane enzymes and cytosolic-membranous signaling and exchange
- outlines antibacterial and hemolytic actions of helical peptides
- emphasizes the structure and function of membranes in oxidative stress and the links to Alzheimer’s disease
- studies membrane-associated proteins involved in autosomal dominant polycystic kidney disease
- focuses on insulin action, the glucose-6-phosphatase enzyme, and cystic fibrosis
- and more!