Fibrositis is a frequent non-specific group of syndrome characterized by diffuse chronic pain, felt in and over muscle masses with focal trigger points or tender points in muscles, joints, tendons and ligaments.It is no longer necessary to find tender trigger points during the exam to make a diagnosis.Fibrositis is a frequent disorder in which a person has long-term pain that is spread throughout the body.Fibrositis has also been linked to fatigue, sleep problems, headaches, depression and anxiety.People with fibrositis may also have tenderness in the joints, muscles, tendons, and other soft tissues.Fibrositis (FS) is typically featured by chronic widespread pain and allodynia (a heightened and painful response to pressure).Fibrositis symptoms are not limited to pain resulting in the use of the alternative term fibromyalgia syndrome for the disorder.Other symptoms are debilitating fatigue, sleep disturbance and joint stiffness.Some people also complain of difficulty with swallowing, bowel and bladder anomalies, numbness and tingling, and poor cognitive function.Fibrositis is often linked with psychiatric disorders such as depression and anxiety and stress-related disorders such as post-traumatic stress disorder.Not all people with fibrositis have all linked symptoms.The exact cause is not known but is believed to involve psychological, genetic, neurobiological and environmental factorsThese same genes are also linked with other functional somatic syndromes and major depressive disorder.Other causes are:GeneticStressSleep disordersPhysical and emotional TraumaDopamine anomalySerotoninHuman growth hormoneDeposition diseaseInfectionChronic fatigue syndromeThe defining symptoms of fibrositis are chronic widespread pain, fatigue, sleep disturbance, and heightened pain in response to tactile pressure (allodynia).Other symptoms may be tingling of the skin (paresthesias), prolonged muscle spasms, weakness in the limbs, nerve pain, muscle twitching, palpitations, and functional bowel disturbances.Many patients have cognitive dysfunctionTreatmentThere is no cure for fibrositis,The purpose of treatment is to help alleviate pain and other symptoms, and to help a person cope with the symptoms.The first type of treatment may require:1. Physical therapy2. Exercise and fitness program3. Stress-relief methods, including light massage and relaxation techniquesIf these treatments do not work, the doctor may also prescribe medicines:The purpose of medication is to improve sleep and pain tolerance.Medicine should be given together with exercise and behavior therapy.1.Anti-seizure medicine2.Analgesics3.Muscle relaxants4.Anti-anxiety, hypnotics5.Antidepressant6.Dopamine agonists7.Central nervous system stimulants8.Combination therapyNon-drug treatment1.Regular floatation tank sessions2.Whirlpool therapyPsychological therapies1.Cognitive behavioral therapy2.Neurofeedback3.Biofeedback and self-managementHealthy lifestyle1.Eat a well-balanced diet2.Avoid caffeine3.Practice good sleep routines to improve quality of sleep4.Stop smoking in smokers.5.Reduce weight in the obese6.Exercise7.Heat to painful areas8.Physical therapy, massage or acupuncture9. Sleep therapy with medicine or aids such as CPAP for sloeep apneaSurgical treatment:Surgery is only indicated in severe cases witha.Limb-threatening ischemiab.Lifestyle-restricting claudicationExperimental treatments1.Milnacipran2.DextromethorphanAlternative therapy1.Massage2.Accupressure3.Nutritional supplements such as magnesium with malic acid and various anti-oxidants to protect the tissuesTABLE OF CONTENTIntroductionChapter 1 FibrositisChapter 2 CausesChapter 3 SymptomsChapter 4 DiagnosisChapter 5 TreatmentChapter 6 PrognosisChapter 7 TendonitisChapter...