Following discovery of the Shoggoth in Antarctica during the ill fated Hobblestone-Thorpe Expedition, sole survivor Sam Oliver has had a difficult time readjusting to his life on Earth as he knew it. Then "Mayday" and "abandoning ship" are the last words heard from Clementine Prioress, the only survivor of a ship that seems to have vanished off the radar, sending Sam Oliver to the South Pacific to save her. Discovery that the ominously fabled R'lyeh has risen is followed by the awakening of dread Cthulu - potentially threatening all life on Earth, starting with humanity.