Ludwig's angina is a rare bacterial infection that infects the floor of the mouth.It normally happens if a tooth infection is left not treated.If the disorder is not promptly treated it can result in severe complications and can be fatal.Ludwig's angina is an acute cellulitis in the area of the sub-mandibular gland.It is most often because of sepsis in the throat or mouth which spreads to the sub-mandibular space.Sometimes, it may be the effect of suppuration in the sub-mandibular gland itself.Ludwig's angina, also called angina ludovici, is a serious, possibly life-threatening cellulitis, or connective tissue infection, of the floor of the mouth, normally happening in adults with concurrent dental infections and if left not treated, may block the airways, requiring tracheostomyLudwig's angina indicates the feeling of strangling, not the feeling of chest pain, though there may be chest pain in Ludwig's angina if the infection spreads into the retro-sternal space.The life-threatening nature of this disorder normally indicates surgical treatment with involvement of critical care doctors such as those found in an intensive care unitIt often forms after an infection of the roots of the teeth (such as tooth abscess) or a mouth injury.Ludwig's angina is bacterial in origin often caused by Streptococcus, Staphylococcus and Bacteroides species.It is mainly caused by infection of the second and third molars as the roots of these teeth have direct entrance to the sub-maxillary space.Other causes of Ludwig's angina are:1. Dental abscesses2. Dental injury or trauma can also produce Ludwig's Angina3. Peritonsillar or parapharyngeal abscesses4. Mandibular fractures5. Oral lacerations and piercings6. Oral cancerPre-disposing factors are:1. Poor oral hygiene2. Dental caries3. Recent dental treatment or tooth extraction4. Underlying systemic disorders such as diabetes, alcoholism, poor immunity, malnutrition etc.Symptoms are:1. Breathing difficulty2. Difficulty swallowing3. Drooling4. Unusual speech (sounds like the person has a "hot potato" in the mouth)5. Tongue swelling or protrusion of the tongue out of the mouth6. Fever7. Neck pain8. Neck swelling9. Redness of the neckThe doctor will do an examination of the neck and head to look for redness and swelling of the upper neck, under the chin.The swelling may extend to the floor of the mouth.The tongue could be swollen or out of place.The patient may require a CT scan.MRI with contrast and CT scan of the head and neck region are done for find out the extent of infection.Fluid cultures are done for detection of the causative organism.Treatments precedence is:1. Airway safety,2. Antibiotic treatment, and3. Surgical drainage.A breathing tube may need to be placed through the mouth or nose and into the lungs to restore breathing.If the swelling blocks the airway, the patient needs to get emergency medical help right away.This is done through an intervention called tracheotomy, where a small opening is created surgically directly into the windpipe through the neckThe surgery called a tracheostomy creates an opening through the neck into the windpipe.In some patients, a tube is inserted through the nose into the lungs for maintaining the airway.Antibiotic medicines are advised for treatment of the underlying bacterial infection.The selection of antibiotic should be broad spectrum and fight against anaerobic, gram-negative and gram positive organisms.The combined usage of penicillin, metronidazole and clindamycin is given until an appropriate antibiotic is chosen after culture and sensitivity.Surgery may be required to drain fluids that are producing the swelling.TABLE OF CONTENTIntroductionChapter 1 Ludwig's AnginaChapter 2 CausesChapter 3...