Thirty-three year old Barry Munday is single minded in his pursuit of casual meaningless sex, but his life changes forever when an unfulfilled sexual encounter with a beautiful teenage girl meets with her angry, trumpet wielding father in a darkened theatre. Upon waking up in a hospital Barry discovers that his most prized possessions, his family jewels, have been stolen. His testicles, irreparably damaged, have been surgically removed. Re-evaluating his life, Barry realizes that work has been something to be avoided, he doesn't particularly like his best friend, and he will never have children. Things seem to go from bad to worse for Barry. He is chased out of a gay bar by a group of midget wrestlers, and his ex-girlfriend's dog has taken to defecating on his front stoop. But Barry is soon lifted from wallowing in a pit of self-despair when Ginger Farley, a woman he can't remember having sexual relations with, sues him for paternity. Ironically through the loss of his testicles Barry is transformed into more of a man than he might have otherwise become.