Six female painters in Renaissance Italy fight to create a work of art inside a Florentine church as they juggle the drama of their personal lives.
In a studiolo behind a church, six women gather to perform an act that is, at once, restorative, powerful, and illegal. They paint. Under the tutelage of Leonardo da Vinci, these six show talent and drive equal to that of any man, but in Renaissance Florence they must hide their skills or risk the scorn of the city.
A commission to paint a fresco in Santo Spirito is announced, and countless artists each seek the fame and glory this job will provide. Viviana, a noblewoman freed from a terrible marriage and now free to pursue her artistic passions in secret, sees a potential opportunity for herself and her fellow female artists. The women first speak to Lorenzo de' Medici, and finally, they submit a bid for the right to paint the fresco. And they win.
But the church will not stand for women painting, especially not in a house of worship. The city is not ready to consider women in positions of power, and in Florence, artists wield tremendous power. Even the women themselves are hesitant; the attention they will bring upon themselves will disrupt their families and could put them in physical danger.
All the while, Viviana grows closer to Sansone, her soldier lover, who is bringing her joy that she never knew with her deceased husband. And fellow-artist Isabetta has her own romantic life to distract her, sparked by Lorenzo himself. Power and passion collide in this sumptuous historical novel of shattering limitations, one brushstroke at a time.