Ben and Mike have never been camping in the Pacific Northwest before, and when their friend Jesse offers to take them on a guided trip, they can't refuse.

Everything goes as planned until they take a fateful hike around a lake bordering the Three Sisters Wilderness Area.

Jesse suddenly falls ill and needs to go back to camp. He hopes a little sleep will beat his illness, as Ben and Mike wait, hoping Jesse will get better.

Then Jesse wakes up.

He is no longer himself, and proceeds to play a game of cat-and-mouse with his friends through the forest over the next few days, battling exhaustion and illness as they all try to survive in the wilderness.