Mika and Yuichiro are finally reunited! With Mika on the brink of death, Yui offers his blood to save his friend's life—which turns Mika into a full-fledged vampire! Meanwhile, the captured Guren is attempting to lead the vampires into a trap set by Kureto, who plans to end this battle once and for all using the Seraph of the End! All groups descend on Nagoya Airport for an all-out war!

After trumpets of the apocalypse proclaim the fall of humanity, vampires arise from the shadows to rule the earth. Yuichiro wants just one thing—to get revenge by killing each and every vampire.