At the Arctic Ocean Pillar, Hyôga faces Isaac, an old friend turned fearsome enemy. At the North Atlantic Pillar, Ikki is attacked by Sea Dragon, Poseidon's right-hand man, who seems strangely familiar. Could the evil Master of Sanctuary, whom the Knights defeated in their first epic battle, have returned to life? Seiya's beloved partner, Marin, confronts Poseidon and is overwhelmed by his godlike power. But Poseidon has yet to fully awaken, and another man controls him...a man the Knights may already know. What happened 13 years ago to set the Battle of the Gods in motion?

The series begins with the story of Seiya, the main hero, who is one of Athena's Knights. Seiya, along with the other Bronze Knights, must train hard to earn their ""Cloths,"" and take on other challenges as well. Knights of the Zodiac (Saint Seiya) has been a hit in Japan (where it is known as simply Saint Seiya), as well as many European countries including Spain, France, and Italy.