有时候，上帝的一个小小玩笑，却令我们终身伤悲。四年前，乔芷珊不告而别，留下叶长卿满世界找她。四年后，为了躲避叶长卿的纠缠，乔芷珊意外地结识了医生郑凯志。他频频拯救她于困境，成为她泅渡彼岸的唯一救赎。直到回到港城，郑凯志如同苍鹰被束缚了翅膀，隐藏的真相被一点点暴露在阳光下。郑凯志的真实身份竟然是郑家的大公子，上一辈的恩怨牵连，已经剑拔弩张。为了躲避孟军山的暗杀，乔芷珊与郑凯志答应救治孟江洋，却在手术即成之日，等来了目的不明的乔伟业。一门之隔，五分钟，却决定着两个人的一生。每一分钟都听见生命在倒数，此生，若还有幸福，必定与你有关。 ( Sometime, the God plays a joke on us but made us sad for the whole life. Four years ago, Qiao Shanzhi left without any notice, leaving Ye Changqing seeking for her around the world. Four years later, to avoid Ye Changqing, she accidentally encountered Doctor Zheng Kaizhi. He frequently saved her from difficulties and became the only redemption to swim to the other side. When back to Gangcheng, Zheng Kaizhi, like a goshawk with wings fastened, gradually unveiled truth into the sunlight. The true figure of Zheng Kaizhi was the eldest son of Zheng's. The feeling of gratitude or resentment of last generation was at a stake. In order to keep away from assassination by Meng Junshan, Qiao Zhishan and Zheng Kaizhi agreed to save Meng Jiangyang; however, on the day of surgery, Qiao Weiye showed up with uncertain purpose. On the other side of the door, the five minute determined the life of two. In each minute, you could hear the countdown of life. In this life, if there is any happiness, it must be related to you. )