There's a new sheriff in town. After five years and one too many tragic incidents, it's time to shake up the NYPD Undead Unit. Captain Mikayla Deigh, a veteran of the police force, steps in to fill that role. When she gets there, however, she finds that the Unit is not what she expected it to be. It's current commanding officer, a zombie cop from the old days, is less concerned about losing his seat than he is about who is taking it over.

On the other side of the bridge, Doctor Denise Luco is finally content. She has a comfortable home that she shares with her son and has escaped the political maneuverings of the government environment. Still, life is not so simple. The research she wants to conduct is blocked at every turn and it seems that her escape from her past is fleeting, if not a complete illusion.