When Jessica Handler was eight years old, her younger sister Susie was diagnosed with leukemia. To any family, the diagnosis would have been upending, but to the Handlers, whose youngest daughter Sarah had been born with a rare congenital blood disorder, it was an unimaginable verdict. By the time Jessica Handler turned nine, she had begun to introduce herself as the “well sibling;” and her family had begun to come apart.

Invisible Sisters is Handler’s powerfully told story of coming of age—as the daughter of progressive Jewish parents who move south to participate in the social-justice movement of the 1960s; as a healthy sister living in the shadow of her siblings’ illness; and as a young woman struggling to step out of the shadow of her sisters’ deaths, to find and redefine herself anew. With keen-eyed sensitivity, Handler’s brave account explores family love and loss, and what it takes not just to survive, but to keep living.