This book is particular in the sense that it applies the concepts of the theory of mining clusters to the analysis of Latin America’s mining industry. The research shows that ultimately the industry’s competitive advantages, like those of any other industry, lie in its capacity to generate knowledge and to innovate. In this view, the book’s case studies have the particularity to deal with knowledge creation and dissemination in the region’s mining clusters. Latin America is home to the least advanced clusters insofar as most if not all of its clusters are lagging behind. The approach used in this book brings to the conclusion that the region’s mining sector will only foster sustainable development if the institutions responsible for local learning are effectively reinforced.