When a young woman falls down a flight of stairs and is left brain dead, her family agrees to donate her organs. Dr. Jesse Travis oversees the grim task, saving several other seriously ill patients. But one of the organ recipients returns to the hospital with a complication no one could have seen coming-West Nile Virus. Soon, other patients who received organs at Community General begin dying of West Nile-related illnesses, and Jesse is suspected as being at fault...

Dr. Mark Sloan knows his friend isn't to blame-and he soon uncovers a conspiracy of greed and personal revenge that may mean the end of his career.