River of Tuscany blends mystery with history in a series of interconnected stories set along the Arno River during pivotal moments of Italy's past. A cryptic guild of hydraulic engineers wields twelve rules of wisdom to alter the course of civilization. Hannibal used them to smash the Romans, Dante to transform Italy's language, and Da Vinci to herald in the Renaissance. Now that ancient criteria have been satisfied, these lessons can be written down and unleashed to the world. Yet a powerful young woman must decide - who will handle this task?