The federal bureaucrat charged with stopping the importation of dangerous materials vanishes only days before enacting a new list of prohibited substances. Homicide detective turned Homeland Security Agent Greg Kane suspects that the HHS employee may have been killed to keep the new list from going into effect, but he has no idea who's behind the crime, which chemical they are so desperate to import, and what they plan to do with it once they've gotten their hands on it.

After he dives into the case Kane discovers a possible link between the official's disappearance and the two-year-old disappearance of Kane's nephew while he was transporting a dangerous federal prisoner. Were the crimes connected? What happened to Kane's nephew, and what does the escaped fugitive plan to do next?