There's a killer on the road...

He's a big rig truck driver who goes by the CB handle White Knuckle, and he's Jack the Ripper on eighteen wheels. For thirty years he has murdered hundreds of women in unimaginable ways, imprisoning them in a secret compartment in his truck, abducting them in one state and dumping their dead bodies across the country.

Dedicated FBI agent Sharon Ormsby is on a mission to hunt down and stop White Knuckle. She goes undercover as a truck driver with a helpful long hauler named Rudy in a cross-country pursuit that will ultimately bring her face-to-face with White Knuckle in a pedal-to-the-metal, high-octane climax on a highway to Hell.