In the distant future, in our own galactic backyard...

With the Confederation on the brink of war, the Watchtower organization struggles to maintain peace despite the ongoing threat of the Secessionists. A killer is picking off Watchmen one by one. Following the philosophy of "Set a thief to catch a thief," Watchman Wisconsin Lockerbie hires cyborg assassin Jersey Jackson to track down the killer. While embroiled in the criminal underworld, they uncover a plot to build a superweapon that will tilt the upcoming conflict in favor of the Secessionists. Lockerbie, Jackson, and a motley crew of misfit aliens must set aside their differences to save the Confederation.