Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation. This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynthetic multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesizing and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation. This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.