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The book is divided into 6 chapters. The first chapter provides a broad overview about apoptosis history, significance and apoptotic cell structure. The second chapter offers a full description of the mechanism of apoptosis followed by the third chapter dealing with the diseases due to apoptosis dysregulation. The fourth chapter discuss the immunological and hormonal relations to apoptosis. The fifth chapter describe the how we can investigate apoptosis. The last chapter provides some of the advanced studies on apoptosis