Advances in Biological and Medical Physics, Volume 15 covers papers on the productive applications of physical science in biology and medicine. The book presents articles dealing with the geometric influence of bone matrix on the differentiation of fibroblasts and information on human repetitious DNA; the complexity of the human genome; and possible directions for future research. The text then describes the problem of biological time. The microcirculatory basis of fluid exchange is also considered. The book concludes with articles dealing with the possibilities for electron microscopy and diffraction of wet, unstained and unfixed biological material, as well as with the metabolic events in localized compartments of the living cell carried out through the use of rapid microspectrofluorometry. Biological and medical physicists and students taking these courses will find the book invaluable.