Blake Drywater is plagued by bullies, doesn't like any of his classes, and hates school in general. All of that changes, however, when he learns that his new science teacher is a wizard. Before long his teacher briefly transforms every student in the class into roaches and earthworms, and magically takes them all to England in the blink of an eye.

But Blake soon learns there is more than science going on in his classroom. An evil wizard is seeking a potion his teacher has made—a potion with enough power to change the world. And when Blake drinks the potion soon thereafter, he finds himself facing problems far harder than any science exam!