While grieving the death of her eccentric nana, Sarah discovers an unexpected gift. She soon grows dependent on the heirloom, a little box, for comfort and guidance. Feeling restless and needing a change, Sarah accepts a job as a traveling hospice nurse and ends up in the quaint, historical town of Camden, South Carolina. Although she loves caring for her patients, loneliness creeps in and threatens to take root. Eventually she opens herself to new friendships, and two remarkable yet vastly differing men compete for her attention. Nate is a true Southerner with a sarcastic wit and genuine warmth, while Dr. Joseph Thornton is a caring oncologist who is known as the best catch in the state.

Facing heart-wrenching trials, the faith of her childhood is all but shattered. In spite of this, Sarah seeks comfort from her box and is determined to cling to Nana's godly legacy. But when a mysterious stranger appears with devastating news, can her cherished box continue to provide answers or will Sarah realize her life has been based on nothing but lies?