Johnny Styles had spent most of his fifty some years partying, drinking, fighting and stumbling through bars, pool halls and the arms of beautiful women without much care. With the death of his best friend, Samantha, contrary to his belief that the world would end, both his life and heart have opened up to let in his estranged family and love for a woman who has been nothing more than a thorn in his side for years.
When his new love Leeny disappears, Johnny sets off on his own to find her. The clues are few and far between, starting off with her old boyfriend, turning to his son and the lunatic he is shacking up with and ending with a serial killer. As the evidence leads in all different directions, with some pointing back at himself, his friends and family continually tell him that Leeny may have just gone off with some other guy to live happily ever after.
Determined to find her, he is beaten, arrested, accused of murder, thrown in a cellar with beady eyed vermin, tormented by Blondie the rat queen, and forced to bet the life of his lover in a game of pool, only to find out that whether he likes it or not, Life Goes On.