In Conceiving Masculinity, Liberty Walther Barnes puts the world of male infertility under the microscope to examine how culturally pervasive notions of gender shape our understanding of disease, and how disease impacts our personal ideas about gender.

Taking readers inside male infertility clinics, and interviewing doctors and couples dealing with male infertility, Barnes provides a rich account of the social aspects of the confusing and frustrating diagnosis of infertility. She explains why men resist a stigmatizing label like "infertile," and how men with poor fertility redefine for themselves what it means to be manly and masculine in a society that prizes male virility. Conceiving Masculinity also details how and why men embrace medical technologies and treatment for infertility.

Broaching a socially taboo topic, Barnes emphasizes that infertility is not just a women's issue. She shows how gender and disease are socially constructed within social institutions and by individuals.