This e-book is a compilation of selected papers on the theme of “Systems, cybernetics and innovation” from the 13th International Congress of the World Organisation of Systems and Cybernetics (WOSC), Slovenia, July 2005 and is guest edited by Professor Matjaz Mulej, University of Maribor. The articles present research and development in a number of areas: Artificial-Natural Dualism; Economic Systems; Education Systems; Engineering and Information Systems; Grey Systems; Management Systems; Mathematical Systems; Nature Systems; Tourism Cybernetics; Viable Organisations; and World Education Systems.