The Savage family is close-knit, but everyone has something to hide—from father Titus's shady business dealings, to mother Angelica's dangerously compulsive shopping habits, to 12-year-old Ivan's increasingly lethal pranks. But teenager Sasha's secret trumps them all: she is dating a vegetarian. This trait will never fly with the rest of the Savages, who are...uniquely carnivorous.
Problems start to pile up. Sasha's boyfriend convinces her to try going vegetarian for a month, but then leaves her for a vegan vigilante. Angelica attempts to pay her mounting credit card bill by allowing commercials to film in the family home, until one of Ivan's pranks leaves a model dead in their bathroom. A detective hired to investigate Titus's predatory business affairs notices the model's disappearance, and starts to think that there may be something more sinister to the perfect-seeming Savages.
He's right, of course—they're cannibals.