Autumn Music is the story of Tess McClure, nee O'Reilly. Born into a traditional Australian/Irish Roman Catholic family, she grows up in a house divided. Her father, an atheist, commits suicide as a result of his experiences in World War I and the loss of his two sons in World War II.

Despite confusion and doubts engendered by life with her father, when Tess marries she anticipates a large family, comfortable domesticity and religious obedience. But, as a result of marital stress, the loss of children and finally the birth of a child with Downs Syndrome, she is compelled to ask uncomfortable questions – and to grow through continuing unforeseen challenges.