Jess Madison has problems. His aging parents seem hell-bent on belittling him in new and increasingly infuriating ways, he's fallen for his best—and, unfortunately, heterosexual—friend David, and his grandmother has recently taken to climbing out on her roof in hopes of contacting the spirit of her late husband, the much-beloved Grandpa Jess.

All Jess wants to do is live his life and feed his goldfish in peace, but instead, he finds himself at the heart of a familial clash that seems ready to tear his family apart. With the help of his two younger brothers, uber-manly AJ and lovably weird Thomas, Jess sets out to reconcile his family, keep Grandma off the roof, and sort out the mess his life has become—with just a little help from Grandpa Jess.