Alice Ott, a retired school teacher turned cyber sleuth, is determined to expose a deadly conspiracy in the nation's Capitol. Alice mobilizes her friends, the Raging Grannies, and persuades her long-lost lover, the handsome microbiologist Gerard, to help her pursue the unsolved mystery of the anthrax letters attack. When Alice and her crew stumble on a bioweapons expert from the epicenter of U.S. bioweapons hiding out in Vermont, they join forces to expose the true origins of the deadly anthrax letters. In taking on the most sinister players in this international cover-up, Alice, Gerard, and a small group of ordinary citizens bravely reveal the darkest secrets of biological weapons, and still make time for love.