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1. Highlights in the History of Cannabis2. Cannabis Use and Misuse3. Stepping Stones, Gateways, and the Prevention of Drug Problems4. Marijuana's Impact on Thought and Memory5. Subjective Effects6. Cannabis Pharmacology7. Marijuana's Health Effects8. Medical Marijuana9. Social Problems: Amotivational Syndrome, Reckless Driving, and Aggression10. Law and Policy11. Treatment for Marijuana Problems12. Final Thoughts