The book Handbook on Basic Laboratory Skills is designed to serve two primary goals: (i) for teaching basic concepts of laboratory techniques and (ii) following good laboratory practices while working in laboratory or doing research. The book presents the importance of laboratory skills/practices and biosafety issues to students and researchers. The chapters included in this book cover information on handling of laboratory chemicals, equipment, preparation of buffers, media, basics of seed testing, biosafety, etc. which constitute curriculum of the course Basic Concepts in Laboratory Techniques (PGS504, 0L + 1P) for Post-Graduate students of the Indian National Agricultural Research System (NARS) including Deemed Universities, State Agricultural Universities (SAUs), and Central Agricultural Universities (CAUs).