The tables have turned, and now Detective Inspector Cass Jones is a wanted man on the streets of London. Framed for murder and hunted by his former colleagues, Cass needs every ally he can get—including a very unexpected figure from his past.
 
While detectives Hask and Ramsey search for the killer behind the lethal Strain II virus, Mr. Bright continues to pull strings from the shadows, and there are dire warnings of a final battle that could tear everything apart.
 
As he searches for his kidnapped nephew while eluding his own pursuers, Cass is determined to find the answers—even if he has to confront the darkest secrets of the history of humanity to do it.