Python has emerged as a powerhouse for DevOps, enabling efficient automation across various stages of software development and deployment. This book bridges the gap between Python programming and DevOps practices, providing a practical guide for automating infrastructure, workflows, and processes, empowering you to streamline your development lifecycle. This book begins with foundational Python concepts and their application in Linux system administration and data handling. Progressing through command line tool development using argparse and Click, package management with pip, Pipenv, and Docker, you will explore automating cloud infrastructure with AWS, GCP, Azure, and Kubernetes. The book covers configuration management with Ansible, Chef, and Puppet, and CI/CD pipelines using Jenkins, GitLab, and GitHub. You will also learn monitoring with Prometheus, Grafana, and OpenTelemetry, MLOps with Kubeflow and MLflow, serverless architecture using AWS Lambda, Azure Functions and Google Cloud Functions, and security automation with DevSecOps practices. The real-world project in this book will ensure the practical application of your learning. By mastering the techniques within this guide, you will gain the expertise to automate complex DevOps workflows with Python, enhancing your productivity and ensuring robust and scalable deployments, making you a highly competent DevOps professional.