Dr. Gabriel Thompson is a world-class neurosurgeon and the youngest to become an attending. Completely dedicated to his career, he has zero social life and has never been in a relationship.

His life turns upside down when he is abducted by Caleb, the bodyguard of a mafia boss. Gabriel's freedom depends on him performing a complex surgery on the boss. But the boss is beyond saving and the failed surgery now puts Gabriel and Caleb on the run.

They forge an unlikely alliance, but the boss' son is after them. Although they're polar opposites, they have to work together to survive. An unexpected passion ignites between Gabriel and Caleb while fighting for their lives, but the odds are against them.