Science-fiction author William Gibson is famously quoted as saying, "The future is already here – it's just not very evenly distributed." During the Covid pandemic, telehealth and remote monitoring were elevated from interesting innovations to essential tools in many healthcare systems, but not all countries had the infrastructure necessary to pivot quickly, amply demonstrating the negative consequences of the digital divide. This book presents the proceedings of MedInfo 2023, the 19th World Congress on Medical and Health Informatics, held from 8 – 12 July 2023 in Sydney, Australia. This series of biennial conferences provides a platform for the discussion of applied approaches to data, information, knowledge, and wisdom in health and wellness. The theme and title of MedInfo 2023 was The Future is Accessible, but the digital divide is a major concern for health and care-informatics professionals, whether because of global economic disparities, digital literacy gaps, or limited access to reliable information about health. A total of 935 submissions were received for the conference, of which 228 full papers, 43 student papers and 117 posters were accepted following a thorough peer-review process involving 279 reviewers. Topics covered include: information and knowledge management; quality, safety and outcomes; health data science; human, organizational and social aspects; and global health informatics. Significant advances in artificial intelligence, machine learning, augmented reality, virtual reality, and genomics hold great hope for future healthcare planning, delivery, management, education, evaluation, and research, and this book will be of interest to all those working to not only exploit the benefits of these technologies, but also to identify ways to overcome their associated challenges.