Spider-Gwen makes a new home for herself in the mainstream Marvel Universe! Gwen Stacy is trapped in the New York of Earth-616 - where she truly becomes a Ghost-Spider! But why did she leave Earth-65 behind to move to the universe where Gwen Stacy died years ago? Why aren't the other spiders meant to know she's here? Why isn't she supposed to suit up? And who will get hurt when she does? You aren't the only one wanting answers: Peter Parker, Miles Morales and Cindy Moon do too! Gwen has had a hard time figuring out who she can trust in her new life - or convincing anyone to trust her. All of which is about to get a whole lot worse as a classic Spider-Foe sets about making everyone see her as a villain!