Blindsided follows Eli as she leads Carla, a local real estate agent, through an election for Key West city mayor. At first, the campaign process appears easy. Despite their differences, the two women work well together. But as time progresses, they face countless obstacles: the Bubba system in the Keys, discrimination from both supporting and opposing forces, and their rapidly intensifying relationship. While Carla starts to doubt her decisions, Eli struggles to find her place in the Keys and in Carla's budding campaign.