Beyond excess, beyond ethics, beyond science. . . . Enter a terrifying new experiment in pain from Eisner Award nominee Cullen Bunn (The Sixth Gun, Basilisk) and acclaimed illustrator Jesús Hervás (The Empty Man)! Dr. Carrie Reynolds was a veteran trauma surgeon with a godlike mastery of muscle and bone. But outside the operating room, her rigidly ordered life spiraled into chaos when her daughter, Heather—a recovering plastic surgery addict—suddenly disappeared, only to mysteriously reemerge in a catatonic state, her vocal cords removed . . . the latest in a series of victims all scarred by a battery of brazenly cruel medical procedures that have baffled police and left an alarming number of once-ordinary citizens maimed, mutilated, or dead on arrival. Because, deep beneath the streets of Carrie's city, a new kind of underground hospital has just opened its doors . . . and, once inside, there are no rules, no oaths, and no taboos too deep to not to be broken. Together, a new class of surgeon has sworn to pierce the final threshold of accepted medical orthodoxy one incision at a time. The scalpel is their tool. The alleys are their operating theater. Murder is their medicine. And only Carrie can stop what they're planning next . . .