This book provides some fundamental information on COVID-19 and its preventive medicine potential by using plant based natural products. The COVID-19 diagnostic approaches and applications, as well as the prediction of number of infected people by predictor models and a mathematical formulation are also provided. This book could stir innovative ideas through the blend of local knowledge and scientific research in the development of various approaches towards treatment and control of COVID-19 and its comorbidity. Its also become a source of ideas for alternative methods of prevention of COVID-19 in the future.