Host–guest chemistry is a cornerstone of supramolecular science, shaping innovations in molecular machines. This book delves into the intricate interplay of molecules, revealing how noncovalent interactions drive technological advancements. Professionals, students, and enthusiasts will discover how host–guest systems revolutionize fields from nanotechnology to biomedicine, making this knowledge invaluable.

Chapters Brief Overview:

1: Host–guest chemistry – The foundation of supramolecular interactions and molecular assembly.

2: Calixarene – Unique cavity structures enabling selective guest encapsulation and applications.

3: Cryptand – Cagelike molecules offering exceptional ion selectivity and binding capabilities.

4: Cucurbituril – Macrocyclic hosts with remarkable stability and biomedical relevance.

5: Clathrate compound – Molecular cages trapping guests for energy, gas storage, and catalysis.

6: Cavitand – Hollow molecular frameworks enhancing selective molecular recognition.

7: Topological drugs – Host–guest principles applied to nextgeneration pharmaceuticals.

8: Molecular sensor – Chemical sensing advancements through host–guest interactions.

9: Resorcinarene – Functionalized macrocycles for versatile host–guest applications.

10: Supramolecular catalysis – Noncovalent catalysis for accelerating chemical transformations.

11: Twodimensional polymer – Layered architectures in supramolecular material design.

12: Molecular recognition – Precise host–guest complementarity in molecular targeting.

13: Cyclodextrin – Versatile cyclic oligosaccharides for pharmaceutical and material science.

14: Supramolecular polymer – Selfassembling macromolecules for dynamic material properties.

15: Noncovalent interaction – Fundamental forces underpinning host–guest chemistry.

16: Supramolecular chemistry – The grand framework of molecular selfassembly and recognition.

17: Halogen bond – Weak but directional interactions influencing molecular organization.

18: Macromolecular cages – Large molecular architectures for selective encapsulation.

19: Coordination cage – Metalorganic frameworks enabling precise molecular hosting.

20: Piinteraction – ππ and πcation interactions shaping molecular stability.

21: Polyrotaxane – Interlocked molecular systems with mechanical functionality.

This book extends beyond theory, linking host–guest chemistry to realworld applications in nanotechnology, biomedicine, and materials science. By mastering these principles, readers unlock a deeper understanding of molecular machines and their transformative potential. The cost of this knowledge pales in comparison to the opportunities it unlocks.